AVPR1B Antibody

Primary Antibodies

Blue Ice

47 kDa

The protein encoded by this gene acts as receptor for
arginine vasopressin. This receptor belongs to the subfamily of
G-protein coupled receptors which includes AVPR1A, V2R and OXT
receptors. Its activity is mediated by G proteins which stimulate a
phosphatidylinositol-calcium second messenger system. The receptor
is primarily located in the anterior pituitary, where it stimulates
ACTH release. It is expressed at high levels in ACTH-secreting
pituitary adenomas as well as in bronchial carcinoids responsible
for the ectopic ACTH syndrome. A spliced antisense transcript of
this gene has been reported but its function is not known.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.

Vasopressin V1b receptor

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.