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Mouse Pak4 Antibody

Mouse Pak4 Antibody

Item no.	PRS-57-745-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Cell Biology Cell Status Flow Cytometry Western Blot Senescence Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Liu, Y., et al. Oncogene 29(44):5883-5894(2010) Tian, Y., et al. Mech. Dev. 126 (8-9), 710-720 (2009) : Ha, U.H., et al. J. Biol. Chem. 283(45):30624-30631(2008) Liu, Y., et al. Mol. Cancer Res. 6(7):1215-1224(2008)
NCBI	Pak4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase PAK 4, p21-activated kinase 4, PAK-4, Pak4, Kiaa1142
Available
Manufacturer - Applications	For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	65 kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Signal Transduction
Background	Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This Mouse Pak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of mouse Pak4.
Clonality	Polyclonal
NCBI Official Name	Serine/threonine-protein kinase PAK 4
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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