RFXAP Antibody

Primary Antibodies

Blue Ice

28 kDa

Major histocompatibility (MHC) class II molecules are
transmembrane proteins that have a central role in development and
control of the immune system. The protein encoded by this gene,
along with regulatory factor X-associated ankyrin-containing
protein and regulatory factor-5, forms a complex that binds to the
X box motif of certain MHC class II gene promoters and activates
their transcription. Once bound to the promoter, this complex
associates with the non-DNA-binding factor MHC class II
transactivator, which controls the cell type specificity and
inducibility of MHC class II gene expression. Mutations in this
gene have been linked to bare lymphocyte syndrome type II,
complementation group D. Transcript variants utilizing different
polyA signals have been found for this gene.

None

batch dependent

For WB starting dilution is: 1:1000

This RFXAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human RFXAP.

Regulatory factor X-associated protein

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.