Comparison

KCNA2 Antibody

Item no. PRS-57-959-400ul
Manufacturer ProSci
Amount 400 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Conjugate/Tag Unconjugated
Citations Denning, E.J., et al. Mol. Membr. Biol. 26(8):397-421(2009)
Peters, C.J., et al. Channels (Austin) 3(5):314-322(2009)
Martos, V., et al. Proc. Natl. Acad. Sci. U.S.A. 106(26):10482-10486(2009)
Stirling, L., et al. Mol. Biol. Cell 20(12):2991-3002(2009)
NCBI KCNA2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Potassium voltage-gated channel subfamily A member 2,NGK1,Voltage-gated K(+) channel HuKIV,Voltage-gated potassium channel HBK5,Voltage-gated potassium channel subunit Kv12,KCNA2
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
57 kDa
Manufacturer - Research Area
Neuroscience
Background
Potassium channels represent the most complex class of
voltage-gated ion channels from both functional and structural
standpoints. Their diverse functions include regulating
neurotransmitter release, heart rate, insulin secretion, neuronal
excitability, epithelial electrolyte transport, smooth muscle
contraction, and cell volume. Four sequence-related potassium
channel genes - shaker, shaw, shab, and shal - have been identified
in Drosophila, and each has been shown to have human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated,
shaker-related subfamily. This member contains six
membrane-spanning domains with a shaker-type repeat in the fourth
segment. It belongs to the delayed rectifier class, members of
which allow nerve cells to efficiently repolarize following an
action potential. The coding region of this gene is intronless, and
the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
By Type
Neuroscience
Modifications
None
Protein Gi #
1345813
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
Immunogen
This KCNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-479 amino acids from the C-terminal region of human KCNA2.
Clonality
Polyclonal
NCBI Official Name
Potassium voltage-gated channel subfamily A member 2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
available

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