ALG11 Antibody

Primary Antibodies

Blue Ice

56 kDa

This gene encodes a
GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1, 2-mannosyltransferase which
is localized to the cytosolic side of the endoplasmic reticulum
(ER) and catalyzes the transfer of the fourth and fifth mannose
residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and
Man4GlcNAc2-PP-dolichol resulting in the production of
Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with
congenital disorder of glycosylation type Ip (CDGIP). This gene
overlaps but is distinct from the UTP14, U3 small nucleolar
ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the
GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1, 2-mannosyltransferase has
been identified on chromosome 19.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This ALG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human ALG11.

GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1, 2-mannosyltransferase

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.