HNRNPD Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are nucleic acid binding proteins and they complex with
heterogeneous nuclear RNA (hnRNA). These proteins are associated
with pre-mRNAs in the nucleus and appear to influence pre-mRNA
processing and other aspects of mRNA metabolism and transport.
While all of the hnRNPs are present in the nucleus, some seem to
shuttle between the nucleus and the cytoplasm. The hnRNP proteins
have distinct nucleic acid binding properties. The protein encoded
by this gene has two repeats of quasi-RRM domains that bind to
RNAs. It localizes to both the nucleus and the cytoplasm. This
protein is implicated in the regulation of mRNA stability.
Alternative splicing of this gene results in four transcript
variants.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.