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ARNT2 Antibody

ARNT2 Antibody

Item no.	PRS-58-559-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies Western Blot Immunofluorescence Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Ramirez, J.M., et al. Eur. J. Immunol. 40(9):2450-2459(2010) Jugessur, A., et al. PLoS ONE(7), E11493 (2010) : Chakrabarti, B., et al. Autism Res 2(3):157-177(2009) Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)
NCBI	ARNT2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Aryl hydrocarbon receptor nuclear translocator 2,ARNT protein 2,Class E basic helix-loop-helix protein 1,bHLHe1,ARNT2,BHLHE1,KIAA0307
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	79 kDa
Manufacturer - Research Area	Cancer, Obesity, Neuroscience
Background	This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
By Type	Cancer, Obesity, Neuroscience
Modifications	None
Protein Gi #	125987793
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen	This ARNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-278 amino acids from the Central region of human ARNT2.
Clonality	Polyclonal
NCBI Official Name	Aryl hydrocarbon receptor nuclear translocator 2
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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