PTPN22 Antibody

Primary Antibodies

Blue Ice

92 kDa

This gene encodes of member of the non-receptor class 4
subfamily of the protein-tyrosine phosphatase family. The encoded
protein is a lymphoid-specific intracellular phosphatase that
associates with the molecular adapter protein CBL and may be
involved in regulating CBL function in the T-cell receptor
signaling pathway. Mutations in this gene may be associated with a
range of autoimmune disorders including Type 1 Diabetes, rheumatoid
arthritis, systemic lupus erythematosus and Graves' disease.
Alternatively spliced transcript variants encoding distinct
isoforms have been described.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This PTPN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-691 amino acids from the C-terminal region of human PTPN22.

Tyrosine-protein phosphatase non-receptor type 22

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.