MSH5 Antibody

Rabbit Ig

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene encodes a member of the mutS family of proteinsthat are involved in DNA mismatch repair and meiotic recombination.This protein is similar to a Saccharomyces cerevisiae protein thatparticipates in segregation fidelity and crossing-over eventsduring meiosis. This protein plays a role in promoting ionizingradiation-induced apoptosis. This protein forms heterooligomerswith another member of this family, mutS homolog 4. Polymorphismsin this gene have been linked to various human diseases, includingIgA deficiency, common variable immunodeficiency, and prematureovarian failure. Alternative splicing results multiple transcriptvariants.

Batch dependent

This MSH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 525-552 amino acids from the Central region of human MSH5.

MutS protein homolog 5

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.