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PDE4A Antibody

PDE4A Antibody

Item no.	PRS-59-005-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Necrosis Cytoskeleton Western Blot Motor proteins Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Selige, J., et al. J. Cell. Physiol. 223(2):317-326(2010) Bjorgo, E., et al. Mol. Cell. Biol. 30(7):1660-1672(2010) Singh, D., et al. Respir. Res. 11, 26 (2010) :
NCBI	PDE4A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cAMP-specific 3',5'-cyclic phosphodiesterase 4A,DPDE2,PDE46,PDE4A,DPDE2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	98 kDa
Manufacturer - Research Area	Cell Cycle, Signal Transduction
Background	Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed 8009369]).
By Type	Cell Cycle, Signal Transduction
Modifications	None
Protein Gi #	116242706
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000
Immunogen	This PDE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human PDE4A.
Clonality	Polyclonal
NCBI Official Name	cAMP-specific 3', 5'-cyclic phosphodiesterase 4A
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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