MAEA Antibody

For WB starting dilution is: 1:1000

blue ice or room temperature

45 kDa

This gene product mediates the attachment of erythroblaststo macrophages. This attachment promotes terminal maturation andenucleation of erythroblasts, presumably by suppressing apoptosis.This protein is an integral membrane protein with the N-terminus onthe extracellular side and the C-terminus on the cytoplasmic sideof the cell. Two immunologically related isoforms of erythroblastmacrophage protein with apparent molecular weights of 33 kD and 36kD were detected in macrophage membranes; this gene encodes thelarger isoform. Multiple alternatively spliced transcript variantsencoding distinct isoforms have been found for this gene, but thebiological validity of some variants has not been determined.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This MAEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-42 amino acids from the N-terminal region of human MAEA.

Macrophage erythroblast attacher

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.