SNAP25 Antibody

Primary Antibodies

Blue Ice

23 kDa

Synaptic vesicle membrane docking and fusion is mediated
by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment
protein receptors) located on the vesicle membrane (v-SNAREs) and
the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE
complex consists of a bundle of four helices, one of which is
supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on
the plasma membrane, the protein syntaxin supplies one helix and
the protein encoded by this gene contributes the other two.
Therefore, this gene product is a presynaptic plasma membrane
protein involved in the regulation of neurotransmitter release. Two
alternative transcript variants encoding different protein isoforms
have been described for this gene.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Zebrafish, Bovine, Chicken, Mouse, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.