SF3B4 Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene encodes one of four subunits of the splicing
factor 3B. The protein encoded by this gene cross-links to a region
in the pre-mRNA immediately upstream of the branchpoint sequence in
pre-mRNA in the prespliceosomal complex A. It also may be involved
in the assembly of the B, C and E spliceosomal complexes. In
addition to RNA-binding activity, this protein interacts directly
and highly specifically with subunit 2 of the splicing factor 3B.
This protein contains two N-terminal RNA-recognition motifs (RRMs),
consistent with the observation that it binds directly to pre-mRNA.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.