EBP Antibody

Primary Antibodies

Blue Ice

26 kDa

The protein encoded by this gene is an integral membrane
protein of the endoplasmic reticulum. It is a high affinity binding
protein for the antiischemic phenylalkylamine Ca2+ antagonist
[3H]emopamil and the photoaffinity label [3H]azidopamil. It is
similar to sigma receptors and may be a member of a superfamily of
high affinity drug-binding proteins in the endoplasmic reticulum of
different tissues. This protein shares structural features with
bacterial and eukaryontic drug transporting proteins. It has four
putative transmembrane segments and contains two conserved
glutamate residues which may be involved in the transport of
cationic amphiphilics. Another prominent feature of this protein is
its high content of aromatic amino acid residues (>23%) in its
transmembrane segments. These aromatic amino acid residues have
been suggested to be involved in the drug transport by the
P-glycoprotein. Mutations in this gene cause Chondrodysplasia
punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This EBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the C-terminal region of human EBP.

3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.