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UBE2L3 Antibody

UBE2L3 Antibody

Item no.	PRS-60-766-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot Primary Antibodies small GTPases Ras Subfamily Rap Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010) Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010) Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010) Purbeck, C., et al. Biochemistry 49(7):1361-1363(2010)
NCBI	UBE2L3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ubiquitin-conjugating enzyme E2 L3,L-UBC,UbcH7,Ubiquitin carrier protein L3,Ubiquitin-conjugating enzyme E2-F1,Ubiquitin-protein ligase L3,UBE2L3,UBCE7,UBCH7
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	18 kDa
Manufacturer - Research Area	Cell Cycle
Background	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
By Type	Cell Cycle
Modifications	None
Protein Gi #	54039805
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For IHC-P starting dilution is: 1:25 For WB starting dilution is: 1:1000
Homology	Predicted species reactivity based on immunogen sequence: Bovine
Immunogen	This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3.
Clonality	Polyclonal
NCBI Official Name	Ubiquitin-conjugating enzyme E2 L3
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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