« Back
Home /
NRG2 Antibody

NRG2 Antibody

Item no.	PRS-62-186-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies Immunohistochemistry Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Yamada, K., et al., Gene 255(1):15-24 (2000). Ring, H.Z., et al., Hum. Genet. 104(4):326-332 (1999). Busfield, S.J., et al., Mol. Cell. Biol. 17(7):4007-4014 (1997). Higashiyama, S., et al., J. Biochem. 122(3):675-680 (1997). Carraway, K.L. III, et al., Nature 387(6632):512-516 (1997).
NCBI	NRG2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2, Neuregulin-2, NRG-2, Divergent of neuregulin-1, DON-1, Neural- and thymus-derived activator for ERBB kinases, NTAK, NRG2, NTAK
Available
Manufacturer - Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	92 kDa
Manufacturer - Research Area	Neuroscience, Signal Transduction
Background	Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Homology	Predicted species reactivity based on immunogen sequence: Rat
Immunogen	This NRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human NRG2.
Clonality	Polyclonal
NCBI Official Name	Pro-neuregulin-2, membrane-bound isoform
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 400 ul

available

Delivery expected until 9/4/2025

Express Delivery: Save 24 days

Compare

Add to wishlist

Get an offer