Drosophila Parkin Antibody

Item no.	PRS-62-278-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	other
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Zhong,L. et al. J. Biol. Chem. 280 (10), 9425-9430 (2005) Pesah,Y. et al. Development 131 (9), 2183-2194 (2004) Haywood,A.F. et al. BMC Neurosci 5, 14 (2004) Finney,N. et al. J. Biol. Chem. 278 (18), 16054-16058 (2003)
NCBI	Q7KTX7
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CG10523-PB; isoform B; Cg10523-pc; isoform c; PARKIN; park; parkin;
Available
Manufacturer - Applications	For WB starting dilution is: 1:1000
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	54 kDa
Background	Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This Drosophila Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the N-terminal region of human Drosophila Parkin.
Clonality	Polyclonal
NCBI Official Name	CG10523-PB, isoform B
NCBI Organism	Drosophila melanogaster
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 10/2/2025

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