Germinal Center Kinase Antibody

Item no.	PRS-62-630-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Metabolism Antibodies By Cell Type Hematology Lymphoma Cell Biology Obesity Cell Status Immunohistochemistry Western Blot Autophagy Primary Antibodies By Organ Pancreatic Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Chadee, D.N., et al., Mol. Cell. Biol. 22(3):737-749 (2002). Katz, P., et al., J. Biol. Chem. 269(24):16802-16809 (1994).
NCBI	MAP4K2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase kinase 2,B lymphocyte serine/threonine-protein kinase,Germinal center kinase,GC kinase,MAPK/ERK kinase kinase kinase 2,MEK kinase kinase 2,MEKKK 2,Rab8-interacting protein,MAP4K2,GCK,RAB8IP
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	92 kDa
Manufacturer - Research Area	Signal Transduction
Background	The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
By Type	Signal Transduction
Modifications	None
Protein Gi #	215274019
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Immunogen	This Germinal Center Kinase (GCK/MAP4K2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-319 amino acids from the Central region of human Germinal Center Kinase (GCK/MAP4K2).
Clonality	Polyclonal
NCBI Official Name	Mitogen-activated protein kinase kinase kinase kinase 2
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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