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PHB2 Antibody

PHB2 Antibody

Item no.	PRS-62-782-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Hematology Lymphoma Cell Biology Obesity Cell Status Immunohistochemistry Western Blot Autophagy Enzymes Fatty Acid Synthesis Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Takata,H., Curr. Biol. 17 (15), 1356-1361 (2007) Kasashima,K., J. Biol. Chem. 281 (47), 36401-36410 (2006)
NCBI	PHB2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Prohibitin-2,B-cell receptor-associated protein BAP37,D-prohibitin,Repressor of estrogen receptor activity,PHB2 {ECO:0000312\|EMBL:AAH147661,ECO:0000312\|HGNC:HGNC:30306}
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	33 kDa
Manufacturer - Research Area	Signal Transduction
Background	PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.
By Type	Signal Transduction
Modifications	None
Protein Gi #	74752151
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Homology	Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen	This PHB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from human PHB2.
Clonality	Polyclonal
NCBI Official Name	Prohibitin-2
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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