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BF Antibody

BF Antibody

Item no.	PRS-62-850-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot Cardiovascular Research Hypertension Primary Antibodies By Organ Colorectal Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Baatz,H., Klin Monatsbl Augenheilkd 226 (8), 654-658 (2009) Goring,K., Am. J. Physiol., Cell Physiol. 296 (5), C1140-C1150 (2009)
NCBI	CFB
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Complement factor B, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, BF, BFD
Available
Manufacturer - Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	86 kDa
Manufacturer - Research Area	Immunology
Background	BF is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Protein Gi #	584908
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the Central region of human BF.
Clonality	Polyclonal
NCBI Official Name	Complement factor B
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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