GCAT Antibody

Item no.	PRS-62-951-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Cell Metabolism Flow Cytometry Immunohistochemistry Western Blot Endocrine Regulation of Lipid Metabolism Oxidative Stress Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Edgar,A.J., Polak,J.M.Eur. J. Biochem. 267 (6), 1805-1812 (2000) Tressel,T., Thompson,R., J. Biol. Chem. 261 (35), 16428-16437 (1986)
NCBI	GCAT
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase, GCAT, KBL
Available
Manufacturer - Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	45 kDa
Manufacturer - Research Area	Obesity, Signal Transduction
Background	The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Homology	Predicted species reactivity based on immunogen sequence: Bovine
Immunogen	This GCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-181 amino acids from the Central region of human GCAT.
Clonality	Polyclonal
NCBI Official Name	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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