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INSC Antibody

INSC Antibody

Item no.	PRS-64-072-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Metabolism Glucose Homeostasis Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Vural, A., et al. Mol. Cell. Biol. 30(6):1528-1540(2010) Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009) Izaki, T., et al. Biochem. Biophys. Res. Commun. 341(4):1001-1006(2006)
NCBI	INSC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein inscuteable homolog,INSC
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	63 kDa
Manufacturer - Research Area	Cell Cycle, Cell Cycle
Background	In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).
By Type	Cell Cycle, Cell Cycle
Modifications	None
Protein Gi #	116248172
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Immunogen	This INSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-437 amino acids from the C-terminal region of human INSC.
Clonality	Polyclonal
NCBI Official Name	Protein inscuteable homolog
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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