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HADHB Antibody

HADHB Antibody

Item no.	PRS-64-152-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies By Cell Type Hematology Leukemia Cell Biology Cell Movement Cell Adhesion Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Purevsuren, J., et al. Mol. Genet. Metab. 98(4):372-377(2009) Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008) Wang, R., et al. Zhonghua Fu Chan Ke Za Zhi 41(10):672-675(2006) Hillier, L.W., et al. Nature 434(7034):724-731(2005)
NCBI	HADHB
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Trifunctional enzyme subunit beta,mitochondrial,TP-beta,3-ketoacyl-CoA thiolase,Acetyl-CoA acyltransferase,Beta-ketothiolase,HADHB
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	51 kDa
Manufacturer - Research Area	Cancer, Obesity, Signal Transduction
Background	HADHB encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
By Type	Cancer, Obesity, Signal Transduction
Modifications	None
Protein Gi #	116241345
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Homology	Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Immunogen	This HADHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-342 amino acids from the C-terminal region of human HADHB.
Clonality	Polyclonal
NCBI Official Name	Trifunctional enzyme subunit beta, mitochondrial
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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