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CD20 Antibody [AISB12]

CD20 Antibody [AISB12]

Item no.	PRS-76-011-0.5mg
Manufacturer	ProSci
Amount	0.5 mg
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Myeloma Flow Cytometry Primary Antibodies By Organ Bladder Cancer Gastric Cancer Lymphatic System Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	FC, FA
Clone	AISB12
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a
Conjugate/Tag	Unconjugated
Citations	Uchida, J., Hamaguchi, Y., Oliver, J. A., Ravetch, J. V., Poe, J. C., Haas, K. M., Tedder, T. F. (2004). The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptordependent mechanisms during anti-CD20 antibody immunotherapy.The Journal of experimental medicine,199(12), 1659-1669. Uchida, J., Lee, Y., Hasegawa, M., Liang, Y., Bradney, A., Oliver, J. A., ... Tedder, T. F. (2004). Mouse CD20 expression and function.International immunology,16(1), 119-129. Qian, J., Zheng, Y., Zheng, C., Wang, L., Qin, H., Hong, S., ... Yi, Q. (2012). Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma.Blood,119(1), 161-169.
NCBI	Ms4a1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cd20,Ly-44,Ms4a2,AA960661,Ms4a1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies, Functional Antibodies
Manufacturer - Isotype	Rat IgG2a
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C . Do not freeze.
Manufacturer - Research Area	Immunology, Functional Assays
Background	The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
By Type	Immunology
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ph7.2.
Manufacturer - Specificity	The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule.
Clonality	Monoclonal
NCBI Official Name	membrane-spanning 4-domains, subfamily A, member 1
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 2/5/2026

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