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CD11a Antibody [HI111]

CD11a Antibody [HI111]

Item no.	PRS-76-153-0.5mg
Manufacturer	ProSci
Amount	0.5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer Renal Cancer Lymphatic System Cancer
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Clone	HI111
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
Citations	Inghirami, G., Wieczorek, R., Zhu, B. Y., Silber, R., Dalla-Favera, R., Knowles, D. M. (1988). Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia.Blood,72(4), 1431-1434. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Bochner, B. S., Luscinskas, F. W., Gimbrone, M. A., Newman, W., Sterbinsky, S. A., Derse-Anthony, C. P., ... Schleimer, R. P. (1991). Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules.The Journal of experimental medicine,173(6), 1553-1557.
NCBI	ITGAL
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD11A, LFA-1, LFA1A, ITGAL
Available
Manufacturer - Isotype	Mouse IgG1, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C . Do not freeze.
Manufacturer - Research Area	Cancer, Functional Assays
Background	The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The heterodimer can bind to CD50 (ICAM-3), CD54 (ICAM-1), and CD102 (ICAM-2).
Purification	The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ph7.2.
Clonality	Monoclonal
NCBI Official Name	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 10/2/2025

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