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CD28 Antibody [JJ319]

CD28 Antibody [JJ319]

Item no.	PRS-76-744-0.5mg
Manufacturer	ProSci
Amount	0.5 mg
Category	Neuroscience Neural Lineage Markers Antibodies Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Clone	JJ319
Specific against	Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
Citations	Nandi, D., Gross, J. A., Allison, J. P. (1994). CD28-mediated costimulation is necessary for optimal proliferation of murine NK cells.The Journal of Immunology,152(7), 3361-3369. Gross, J. A., Callas, E. L. E. N. I., Allison, J. P. (1992). Identification and distribution of the costimulatory receptor CD28 in the mouse.The Journal of Immunology,149(2), 380-388. Nishio, M., Spielman, J., Lee, R. K., Nelson, D. L., Podack, E. R. (1996). CD80 (B7. 1) and CD54 (intracellular adhesion molecule-1) induce target cell susceptibility to promiscuous cytotoxic T cell lysis.The Journal of Immunology,157(10), 4347-4353.
NCBI	Cd28
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD28RNA, Cd28
Available
Manufacturer - Isotype	Mouse IgG1
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C . Do not freeze.
Manufacturer - Research Area	Immunology, Functional Assays
Background	The JJ319 monoclonal antibody specifically reacts with rat CD28, a 44 kDa glycoprotein member of the immunoglobulin superfamily. CD28 is expressed on alpha/beta TCR+ T cells, some gamma/delta TCR+ T cells and a subset of NK cells. CD28 is a costimulatory receptor required for T cell activation. Its ligands are CD80 (B7-1) and CD86 (B7-2).
Purification	The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ph7.2.
Clonality	Monoclonal
NCBI Official Name	Cd28 molecule
NCBI Organism	Rattus norvegicus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 9/4/2025

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