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CD161 Antibody [HP-3G10] (APC)

CD161 Antibody [HP-3G10] (APC)

Item no.	PRS-76-840-100tests
Manufacturer	ProSci
Amount	100 tests
Category	Neuroscience Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	FC
Clone	HP-3G10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	APC
Citations	Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., van der Merwe, P. A. (1997).The leucocyte antigen factsbook. Academic Press. Lindsten, T., Lee, K. P., Harris, E. S., Petryniak, B., Craighead, N., Reynolds, P. J., ... Gray, G. S. (1993). Characterization of CTLA-4 structure and expression on human T cells.The Journal of Immunology,151(7), 3489-3499. Kuiper, H. M., Brouwer, M., Linsley, P. S., Van Lier, R. A. (1995). Activated T cells can induce high levels of CTLA-4 expression on B cells.The Journal of Immunology,155(4), 1776-1783.
NCBI	KLRB1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	NKR,CD161,CLEC5B,NKR-P1,NKRP1A,NKR-P1A,hNKR-P1A,KLRB1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Mouse IgG1, kappa
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Innate Immunity, Immunology
Background	The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gammadelta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.
By Type	Innate Immunity, Immunology
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity	The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A.
Clonality	Monoclonal
NCBI Official Name	killer cell lectin-like receptor subfamily B, member 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 tests

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Delivery expected until 11/6/2025

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