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CD144 Antibody [16B1] (PE)

CD144 Antibody [16B1] (PE)

Item no.	PRS-76-861-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Neuroscience Neural Lineage Markers Neural Adhesion Molecules Antibodies Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	FC
Clone	16B1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	PE
Citations	Corada, M., Mariotti, M., Thurston, G., Smith, K., Kunkel, R., Brockhaus, M., ... Dejana, E. (1999). Vascular endothelialcadherin is an important determinant of microvascular integrity in vivo.Proceedings of the National Academy of Sciences,96(17), 9815-9820. Crosby, C. V., Fleming, P. A., Argraves, W. S., Corada, M., Zanetta, L., Dejana, E., Drake, C. J. (2005). VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly.Blood,105(7), 2771-2776. May, C., Doody, J. F., Abdullah, R., Balderes, P., Xu, X., Chen, C. P., ... Bohlen, P. (2005). Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature.Blood,105(11), 4337-4344.
NCBI	CDH5
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	7B4,CD144,CDH5
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Mouse IgG1
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Cancer
Background	The 16B1 monoclonal antibody specifically reacts with human CD144, the 140 kDA molecule called vascular endothelial (VE-cadherin) or cadherin 5. CD144 is an endothelial specific calcium-dependent adhesion molecule involved in cell contact-dependent growth inhibition, migration, survival, adhesion. It is concentrated at the intercellular boundaries of endothelial cells and essential in maintaining cell layer integrity.
By Type	Cancer
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity	The 16B1 monoclonal antibody specifically reacts with human CD144, the 140 kDA molecule called vascular endothelial (VE-cadherin) or cadherin 5.
Clonality	Monoclonal
NCBI Official Name	cadherin 5, type 2 (vascular endothelium)
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 11/6/2025

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