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CD184 Antibody [2B11] (PE)

CD184 Antibody [2B11] (PE)

Item no.	PRS-76-872-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Flow Cytometry Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Heart & Blood Cancer Renal Cancer Lymphatic System Cancer
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Clone	2B11
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Conjugate/Tag	PE
Citations	Pierelli, L., Bonanno, G., Rutella, S., Marone, M., Scambia, G., Leone, G. (2001). CD105 (endoglin) expression on hematopoietic stem/progenitor cells.Leukemia lymphoma,42(6), 1195-1206. She, X., Matsuno, F., Harada, N., Tsai, H., Seon, B. K. (2004). Synergy between anti‐endoglin (CD105) monoclonal antibodies and TGF‐-beta in suppression of growth of human endothelial cells.International journal of cancer,108(2), 251-257. Seon, B. K., Kumar, S. (2002). CD105 antibody for targeting of tumor vascular endothelial cells. InThe new angiotherapy(pp. 499-515). Humana Press.
NCBI	Cxcr4
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1
Available
Manufacturer - Isotype	Rat IgG2b, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Stem Cell, Chemokines & Cytokines, Growth Factors
Background	The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	chemokine (C-X-C motif) receptor 4
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 9/4/2025

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