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CD146 Antibody [P1H12] (PE)

CD146 Antibody [P1H12] (PE)

Item no.	PRS-76-886-25tests
Manufacturer	ProSci
Amount	25 tests
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Protein Aggregation, Clearance & Misfolding Antibodies Flow Cytometry Primary Antibodies By Organ Skin Cancer Bone Cancer Adhesion Molecule Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	FC
Clone	P1H12
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	PE
Citations	Chen, J. W., Cha, Y. I. N. G., Yuksel, K. U., Gracy, R. W., August, J. T. (1988). Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens.Journal of Biological Chemistry,263(18), 8754-8758. Grtzkau, A., Smorodchenko, A., Lippert, U., Kirchhof, L., Artuc, M., Henz, B. M. (2004). LAMP‐1 and LAMP‐2, but not LAMP‐3, are reliable markers for activation‐induced secretion of human mast cells.Cytometry Part A,61(1), 62-68. Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J. J., Van den Brule, F., Castronovo, V., ... Coninck, W. D. (1998). Expression of Lamp‐1 and Lamp‐2 and their interactions with galectin‐3 in human tumor cells.International journal of cancer,75(1), 105-111.
NCBI	Mcam
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD146,CD149,Muc18,s-endo,AV025631,1-gicerin,s-gicerin,Mcam
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Mouse IgG1, kappa
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Background	The P1H12 monoclonal antibody reacts with CD146, 118kDA transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo. It is a prominently glycosylated protein with carbohydrates comprising the majority of its mass and it is expressed on melanoma, stromal, endothelial, and bone marrow fibroblasts. The P1H12 antibody cross reacts with human, mouse, canine, rabbit to the exclusion of rat protein.
By Type	Other
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity	The P1H12 monoclonal antibody reacts with CD146, 118kDA transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo.
Clonality	Monoclonal
NCBI Official Name	melanoma cell adhesion molecule
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 tests

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Delivery expected until 11/6/2025

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