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CD282 Antibody [TL2.1] (FITC)

CD282 Antibody [TL2.1] (FITC)

Item no.	PRS-76-947-25tests
Manufacturer	ProSci
Amount	25 tests
Category	Neuroscience Neural Lineage Markers Antibodies Flow Cytometry Primary Antibodies Neurodegeneration Markers
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Clone	TL2.1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Conjugate/Tag	FITC
Citations	Flo, T. H., Halaas, ., Lien, E., Ryan, L., Teti, G., Golenbock, D. T., ... Espevik, T. (2000). Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.The Journal of Immunology,164(4), 2064-2069. Lien, E., Sellati, T. J., Yoshimura, A., Flo, T. H., Rawadi, G., Finberg, R. W., ... Golenbock, D. T. (1999). Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.Journal of Biological Chemistry,274(47), 33419-33425. Cook, E. B., Stahl, J. L., Esnault, S., Barney, N. P., Graziano, F. M. (2005). Toll-like receptor 2 expression on human conjunctival epithelial cells: a pathway for
NCBI	TLR2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TIL4, CD283, TLR2
Available
Manufacturer - Isotype	Mouse IgG2a, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Innate Immunity
Background	The TL2.1 monoclonal antibody specifically reacts with human CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on peripheral blood monocytes and is involved distinguishing bacterial lipoproteins. The TL2.1 antibody blocks the receptor and immunoprecipitates TLR2 from human mammary epithelial cells (HMEC) and peripheral blood mononuclear cells (PBMC).
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	toll-like receptor 2
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 tests

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Delivery expected until 9/4/2025

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