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CD289 Antibody [72-1665] (PE)

CD289 Antibody [72-1665] (PE)

Item no.	PRS-76-971-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Renal Cancer
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Clone	72-1665
Specific against	Human (Homo sapiens)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	PE
Citations	Zhang, J. Y., Zhang, Z., Wang, X., Fu, J. L., Yao, J., Jiao, Y., ... Wang, F. S. (2007). PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors.Blood,109(11), 4671-4678. Bennett, F., Luxenberg, D., Ling, V., Wang, I. M., Marquette, K., Lowe, D., ... Carreno, B. M. (2003). Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses.The Journal of Immunology,170(2), 711-718. Thompson, R. H., Dong, H., Lohse, C. M., Leibovich, B. C., Blute, M. L., Cheville, J. C., Kwon, E. D. (2007). PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma.Clinical Cancer Research,13(6), 1757-1761.
NCBI	TLR9
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TLR9, TLR9
Available
Manufacturer - Isotype	Rat IgG2a, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Innate Immunity
Background	The 72-1665 monoclonal antibody specifically reacts with CD289, also known as human toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	toll-like receptor 9
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 10/2/2025

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