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IL-17A Antibody [17B7] (FITC)

IL-17A Antibody [17B7] (FITC)

Item no.	PRS-77-005-0.025mg
Manufacturer	ProSci
Amount	0.025 mg
Category	Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	FC
Clone	17B7
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	FITC
NCBI	Il17a
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Il17,Ctla8,IL-17,Ctla-8,IL-17A,Il17a
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rat IgG2a, kappa
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Immunology, Chemokines & Cytokines, Growth Factors
Background	The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.
By Type	Immunology, Chemokines & Cytokines, Growth Factors
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity	The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine.
Clonality	Monoclonal
NCBI Official Name	interleukin 17A
NCBI Organism	Mus musculus; Rattus norvegicus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.025 mg

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Delivery expected until 11/6/2025

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