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LPAM-1 Antibody [DATK32] (APC)

LPAM-1 Antibody [DATK32] (APC)

Item no.	PRS-77-141-0.025mg
Manufacturer	ProSci
Amount	0.025 mg
Category	Oncology Neuroscience Neuroinflammation Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies By Organ Renal Cancer Bone Cancer
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Clone	DATK32
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Conjugate/Tag	APC
NCBI	Itga4
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD49D, Itga4B, Itga4
Available
Manufacturer - Isotype	MouseIgG2a, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Immunology
Background	The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mousealpha4beta7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa alpha4 and the 130 kDa beta7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the alpha4beta7 integrin heterodimer. alpha4beta7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the alpha4beta7 induces the alpha4beta7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	integrin alpha 4
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.025 mg

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Delivery expected until 10/2/2025

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