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p62Dok (phospho Tyr362) Antibody

p62Dok (phospho Tyr362) Antibody

Item no.	PRS-79-223-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Colorectal Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Zhou Songyang, et al. (2001) J. Biol. Chem ; 276: 2459 - 2465. Jean-Guy Nemorin, et al. (2000) J. Biol. Chem ; 275: 14590. Yuji Yamanashi, et al. (2000) Genes & Dev ; 14: 11. Ibuki Kato, et al. (2002) J. Immunol ; 168: 629.
NCBI	DOK1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	P62DOK,PRKCT,DOK1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store antibody at -20˚ C for up to one year.
Molecular Weight	62 kDa
Manufacturer - Research Area	Phospho-Specific
Background	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
By Type	Phospho-Specific
Modifications	Phospho-Specific
Protein Gi #	4503357
Purification	Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration	1 mg/mL
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note	Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Manufacturer - Specificity	This antibody detects endogenous level of p62Dok only when phosphorylated at tyrosine 362.
Immunogen	p62Dok (phospho-Tyr362) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 362 (P-I-Y (p) -D-E) derived from Human p62Dok.
Clonality	Polyclonal
NCBI Official Name	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 2/5/2026

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