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PI3K P85 (phospho Tyr467) Antibody

PI3K P85 (phospho Tyr467) Antibody

Item no.	PRS-79-505-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot Cardiovascular Research Myocardial Infarction Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Stoyanov, B. et al. (1995) Science 269, 690-3. Simpson, L. and Parsons, R. (2001) Exp Cell Res 264, 29-41. Neri, L. M. et al. (2002) Biochim Biophys Acta 1584, 73-80.
NCBI	PIK3R1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	p85, AGM7, GRB1, p85-ALPHA, LHR, MDU2, MDU3, MIC4, PI3-kinase p85 subunit alpha, PtdIns-3-kinase p85-alpha
Available
Manufacturer - Applications	Western Blot: 1:500~1:1000
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store antibody at -20°C for up to one year.
Molecular Weight	85 kDa
Manufacturer - Research Area	Phospho-Specific
Background	Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
Modifications	Phospho-Specific
Protein Gi #	32455252 / 166795247 / 4826908
Purification	Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration	1 mg/ml
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen	PI3K P85 (phospho-Tyr467) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 467 (L-Y (p) -E-E-Y) derived from Human PI3K P85.
Clonality	Polyclonal
NCBI Official Name	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/4/2025

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