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Bcl-2 Antibody [10C4]

Bcl-2 Antibody [10C4]

Item no.	PRS-99-624-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Flow Cytometry Autophagy Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	FC
Clone	10C4
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
NCBI	Bcl2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	B cell leukemia 2
Available
Manufacturer - Applications	Bcl-2 Antibody [10C4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store vial at 2-8°C
Manufacturer - Research Area	Cancer, Obesity, Signal Transduction
Background	Bcl-2 is a 26 kDa member of the family of proteins involved in regulation of programmed cell death, or apoptosis. It is expressed in a variety of both normal and neoplastic tissues and appears to be membrane-bound since it is detectable in crude membrane and nuclear fractions, but not in the soluble fraction of cell lysates. Overexpression of Bcl-2 can prevent apoptosis, while formation of heterodimers with Bax, another Bcl-2-related protein, inhibits Bcl-2’s ability to promote cell survival.
Concentration	0.1 mg/mL
Buffer	Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Immunogen	Murine Bcl-2 peptide (a.a. 61-76)
Clonality	Monoclonal
NCBI Official Name	B cell leukemia/lymphoma 2
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 10/2/2025

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