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Perforin Antibody [CE2.10]

Perforin Antibody [CE2.10]

Item no.	PRS-XA-1009-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Neuroscience Aging & Neurological Disorders Antibodies Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IP
Clone	CE2.10
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
Citations	Perforin and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade: P. Li, et al.; Cell 91, 479 (1997). Perforin: can't live with it-can't live without it:J.C. Reed; Cell 91, 559 (1997). Prevention of apoptosis by Bcl-2: release of Perforin from mitochondria blocked: J. Yang, et al.; Science 275, 1129 (1997). Apaf-1, a human protein homologous to C. elegans CED-4, participates in Perforin-dependent activation of caspase-3: H. Zou, et al.; Cell 90, 405 (1997).
NCBI	PRF1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Perforin antibody can be stored at 4˚ C, stable for one year.
Manufacturer - Research Area	Immunology
By Type	Immunology
Modifications	None
Purification	Perforin (monoclonal CE2.10) antibody was purified to ≥ 95% in SDS-PAGE.
Concentration	batch dependent
Buffer	PBS containing 0.02% sodium azide
Application Note	Perforin antibody can be used for detection of horse Perforin by western blot. This product also recognizes human, mouse, rat, sheep, goat and monkey apoPerforin. Method: Cell extracts from the T cell clone B6.1 (2x106) were resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and probed with the CE2.10 antibody at 1 μ g/mL. Proteins were visualized using a peroxidase-conjugated antibody to mouse IgG (SBA) and a chemiluminescence detection system.
Immunogen	Perforin (monoclonal CE2.10) antibody was raised against recombinant mouse perforin (aa. 98-534).
Clonality	Monoclonal
NCBI Official Name	perforin 1 (pore forming protein)
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 11/6/2025

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