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Anti-Integrin alpha-M (CD11b, ΜΑC-1, OX-42 Antigen) Antibody

Anti-Integrin alpha-M (CD11b, ΜΑC-1, OX-42 Antigen) Antibody

Item no.	MAC
Manufacturer	Aves Labs
Amount	1000 uL
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Chicken
Isotype	IgY
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD antigen CD11b
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Category	Cell Adhesion Molecules, Cell Markers, Glial and Schwann Cell Markers
Manufacturer - Targets	Integrin Alpha M
Country of Origin	United States
Storage Conditions	Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
Molecular Weight	170 kDa
Concentration	100 µg/mL
Buffer	Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS, " pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
Quality Control	Antibodies were analyzed by immunohistochemistry (at a concentration of 3 µg/mL) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution, Aves Labs Cat.# F-1005) or HRP-labeled goat anti-chicken IgY (1:2000 dilution, Aves Labs, Cat.# H-1004) as the secondary reagent.
Description	Our anti-Integrin Alpha-M (MAC-1) antibody was purified from eggs collected from chickens injected with a KLH-conjugated peptide corresponding to a sequence shared between the mouse (NP_001076429.1) and human gene products (NP_001139280.1). These antibodies have been validated with human, mouse and rat tissues.
Manufacturer - Statement	We produce our Anti-Integrin Alpha M chicken polyclonal primary antibody. It is great in IHC, ICC, WB and is affinity-purified IgY.
Target Description	Integrin Alpha M (also known as MAC-1 and CD11b) is a 1142 amino acid protein expressed in various antigen-presenting cells of the immune system, including microglial cells of the central nervous system. This is the same protein that is recognized by the Ox-42 mouse monoclonal antibody.
Antibody Registry ID (RRID)	AB_2313548
Clonality	Polyclonal
Dilution Range ICC	1:2000-1:5000
Dilution Range IHC	1:2000-1:5000
Dilution Range Western Blot	1:2000-1:5000
Immunogen	Synthetic peptide
Immunogen Species	Human, Mouse
Manufacturer - Form	Affinity-Purified IgY
Expiration	12 months from receipt of product
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Production Notes	Chickens were immunized with a Keyhole Limpet Hemocyanin (KLH)-conjugate of a synthetic peptide corresponding to a region near the center of the extracellular domain of this single-membrane pass gene product). After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column to which the same peptide was attached. Finally, the antibody concentration was adjusted to 100 µg/mL and filter-sterilized.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1000 uL

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Delivery expected until 11/13/2025

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