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Anti-Human CD32 SAFIRE Purified

Anti-Human CD32 SAFIRE Purified

Item no.	04411-25-50
Manufacturer	BioGems
Amount	50 ug
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	6C4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	VELY, F., GRUEL, N., MONCUIT, J., COCHET, O., ROUARD, H., DARE, S., ... & TEILLAUD, J. L. (1997). A new set of monoclonal antibodies against human FcγRII (CD32) and FcγRIII (CD16): characterization and use in various assays. Hybridoma, 16(6), 519-528. Liebert, M. A. (1997). 6C4, 2B2, 3D3. Hybridoma, 16(6). Bouhlal, H., Martinvalet, D., Teillaud, J. L., Fridman, C., Kazatchkine, M. D., Bayry, J., ... & Kaveri, S. V. (2014). Natural Autoantibodies to Fcγ Receptors in Intravenous Immunoglobulins. Journal of clinical immunology, 1-8.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 6C4 monoclonal antibody specifically recognizes two isoforms of human CD32, Fc gamma RIIA and Fc gamma RIIB. From alternative mRNA splicing, 6 isoforms of CD32 have been reported. CD32 is a 40 kDA polymorphic transmembrane glycoprotein expressed on monocytes, macrophages, graulocytes, B cells, and platelets. The receptor has low affinity toward IgG and is involved in immunomodulation, phagocytosis, and the inflammation response. The 6C4 antibody in a rosette blocking assay is reported to inhibit Ig binding
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Inflammation
Format	SAFIRE Purified

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Request Data Sheet

04411-25-50-datasheet.pdf

04411-25-50-safety-datasheet.pdf