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Anti-Human CD62L (L-Selectin) PE

Anti-Human CD62L (L-Selectin) PE

Item no.	04731-60-25
Manufacturer	BioGems
Amount	25 tests
Category	Neuroscience Neural Lineage Markers Neuroinflammation Neural Signaling Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies
Type	Antibody
Format	PE
Applications	FC
Clone	DREG-56
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	PE
Citations	Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Kishimoto, T. K., Jutila, M. A., & Butcher, E. C. (1990). Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule. Proceedings of the National Academy of Sciences, 87(6), 2244-2248. Kishimoto, T. K., Warnock, R. A., Jutila, M. A., Butcher, E. C., Lane, C., Anderson, D. C., & Smith, C. W. (1991). Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro. Blood, 78(3), 805-811.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1. It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). CD62L is expressed on monocytes, NK cells, neutrophils, granulocytes, and subsets of T and B cells. It is reported that the DREG-56 antibody inhibits the binding of lymphocytes to HEV tissue in frozen peripheral tissue.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Adaptive Immunity, Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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04731-60-25-datasheet.pdf

04731-60-25-safety-datasheet.pdf