Anti-Human CD45 APC-Cyanine7

Item no.	07111-87-25
Manufacturer	BioGems
Amount	25 tests
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Primary Antibodies By Organ Bone Cancer Progenitor Markers
Type	Antibody
Format	APC-Cy7
Applications	FC
Clone	HI30
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	APC
Citations	Knapp WA (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Ninomiya, M., Abe, A., Katsumi, A., Xu, J., Ito, M., Arai, F., ... & Naoe, T. (2006). Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice. Leukemia, 21(1), 136-142. Yoshino, N., AMI, Y., TERAO, K., TASHIRO, F., & HONDA, M. (2000). Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Experimental Animals, 49(2), 97-110.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The HI30 monoclonal antibody specifically reacts with the 180 kDa, 190 kDa, 205 kDa, and 220 kDa isoforms of the human leukocyte common antigen (LCA) CD45. It is expressed on lymphocytes, granulocytes, monocytes, thymocytes, and eosinophils, but not on mature erythrocytes, platelets, mature erythroid cells of bone marrow, and non-hematopoietic tissues. CD45 is essential for T cell activation and the tyrosine phosphatase activity of its intracellular region is integral for signal transduction.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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07111-87-25-datasheet.pdf

07111-87-25-safety-datasheet.pdf