Comparison

Anti-Human CD25 PE

Item no. 07311-60-25
Manufacturer BioGems
Amount 25 tests
Category
Type Antibody
Format PE
Applications FC
Clone BC96
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Conjugate/Tag PE
Citations Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York
Zhang, B., Zhang, X., Tang, F. L., Zhu, L. P., Liu, Y., & Lipsky, P. E. (2008). Clinical significance of increased CD4+ CD25-Foxp3+ T cells in patients with new-onset systemic lupus erythematosus. Annals of the rheumatic diseases,67(7), 1037-1040.
Chapel, A., Bensussan, A., Vilmer, E., & Dormont, D. (1992). Differential human immunodeficiency virus expression in CD4+ cloned lymphocytes: from viral latency to replication. Journal of virology, 66(6), 3966-3970.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Description
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor α (IL-2R α, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor β chain (CD122) and the common γ chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.

Storage Temperature
4C
Formulation
Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation
The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest
Adaptive Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 tests
Available: In stock
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