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Anti-Human CD95 (APO-1/Fas) SAFIRE Purified

Anti-Human CD95 (APO-1/Fas) SAFIRE Purified

Item no.	08011-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	EOS9.1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgM Kappa
Citations	Nagata, S., & Golstein, P. (1995). The Fas death factor. Science, 267(5203), 1449-1456. Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998. Zhang, P., Sun, D., Ke, Y., Kaplan, H. J., & Shao, H. (2007). The net effect of costimulatory blockers is dependent on the subset and activation status of the autoreactive T cells. The Journal of Immunology, 178(1), 474-479.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Monocytes and Macrophages, NK and NKT Cells
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

08011-25-500-datasheet.pdf

08011-25-500-safety-datasheet.pdf