Anti-Human CD16 FITC

Item no.	08211-50-25
Manufacturer	BioGems
Amount	25 tests
Category	Oncology Metabolism Diabetes Antibodies Flow Cytometry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Format	FITC
Applications	FC
Clone	CB16
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	FITC
Citations	Deaglio, S., Zubiaur, M., Gregorini, A., Bottarel, F., Ausiello, C. M., Dianzani, U., ... & Malavasi, F. (2002). Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells. Blood, 99(7), 2490-2498. Peruzzi, G., Femnou, L., Gil-Krzewska, A., Borrego, F., Weck, J., Krzewski, K., & Coligan, J. E. (2013). Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells. The Journal of Immunology, 191(4), 1883-1894. Wirthmueller, U., Kurosaki, T., Murakami, M. S., & Ravetch, J. V. (1992). Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain. The Journal of experimental medicine, 175(5), 1381-1390.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The CB16 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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08211-50-25-datasheet.pdf

08211-50-25-safety-datasheet.pdf