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Anti-Human CD59 (Protectin) PE

Anti-Human CD59 (Protectin) PE

Item no.	11611-60-25
Manufacturer	BioGems
Amount	25 tests
Category	Neuroscience Neuroinflammation Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	PE
Applications	FC
Clone	OV9A2
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	PE
Citations	Deckert, M., Kubar, J., Zoccola, D., Bernard-Pomier, G., Angelisova, P., Horejsi, V., & Bernard, A. (1992). CD59 molecule: a second ligand for CD2 in T cell adhesion. European journal of immunology, 22(11), 2943-2947. Korty, P. E., Brando, C. L. A. R. A., & Shevach, E. M. (1991). CD59 functions as a signal-transducing molecule for human T cell activation. The Journal of immunology, 146(12), 4092-4098. Davies, A., Simmons, D. L., Hale, G., Harrison, R. A., Tighe, H., Lachmann, P. J., & Waldmann, H. (1989). CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. The Journal of experimental medicine, 170(3), 637-654.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The OV9A2 monoclonal antibody specifically reacts with human CD59 (Protectin), a 19-25 kDA GPI-anchored glycoprotein. CD59 is expressed on hematopoietic and non-hematopoietic cells including lymphocytes, granulocytes, erythrocytes, monocytes and neurons. CD59 can inhibit complement cytolytic activity and the assembly of the membrane attack complex when bound to C8 and C9 complement components. It is involved in T cell activation and modulates T cell adhesion through interaction with CD2.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity, Adaptive Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

11611-60-25-datasheet.pdf

11611-60-25-safety-datasheet.pdf