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Anti-Human CD197 (CCR7) PE

Anti-Human CD197 (CCR7) PE

Item no.	20011-60-100
Manufacturer	BioGems
Amount	100 tests
Category	Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	PE
Applications	FC
Clone	3D12
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	PE
Citations	Sallusto, F., Lenig, D., Färster, R., Lipp, M., & Lanzavecchia, A. (1999). Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature, 401(6754), 708-712. Yoshida, R., Nagira, M., Imai, T., Baba, M., Takagi, S., Tabira, Y., ... & Yoshie, O. (1998). EBI1-ligand chemokine (ELC) attracts a broad spectrum of lymphocytes: activated T cells strongly up-regulate CCR7 and efficiently migrate toward ELC. International immunology, 10(7), 901-910. Lee, N., Llano, M., Carretero, M., Ishitani, A., Navarro, F., Lapez-Botet, M., & Geraghty, D. E. (1998). HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Proceedings of the National Academy of Sciences,95(9), 5199-5204.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor. We recommend that this antibody be incubated for at least 45 minutes at 4°C for optimal staining.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity, Cytokines & Growth Factors, Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

20011-60-100-datasheet.pdf

20011-60-100-safety-datasheet.pdf