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Anti-Human CD138 (Syndecan-1) PE

Anti-Human CD138 (Syndecan-1) PE

Item no.	20411-60-100
Manufacturer	BioGems
Amount	100 tests
Category	Oncology Neuroscience Metabolism Diabetes Targets for Rodent Neurosciences Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Carcinoma Hematology Myeloma Flow Cytometry Primary Antibodies By Organ Skin Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	DL-101
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	PE
Citations	Gattei, V., Godeas, C., Degan, M., Rossi, F. M., Aldinucci, D., & Pinto, A. (1999). Characterization of anti-CD138 monoclonal antibodies as tools for investigating the molecular polymorphism of syndecan-1 in human lymphoma cells. British journal of haematology, 104(1), 152-162. Fitzgerald, M. L., Wang, Z., Park, P. W., Murphy, G., & Bernfield, M. (2000). Shedding of syndecan-1 and-4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-"sensitive metalloproteinase. The Journal of cell biology, 148(4), 811-824. Itoua Maiga, R., Lemieux, J., Roy, A., Simard, C., & Neron, S. (2014). Flow Cytometry Assessment of In Vitro Generated CD138< b>< sup>. BioMed research international, 2014.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The DL-101 monoclonal antibody specifically reacts with human CD138, a 85-92 kDA type I heparan sulfate proteoglycan. CD138 is known as Syndecan-1 and is expressed on pre-B cells, immature B cells, plasma cells, and malignant plasma cells, to the exclusion of mature circulating B cells. Syndecan-1 is also expressed on vascular smooth muscle, endothelial, neural, and embryonic mesenchymal cells. It is involved in cellular proliferation, cellular migration, and acts as an extracellular matrix receptor. Among the hematopoietic elements, CD138 is a useful marker for plasma cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

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20411-60-100-datasheet.pdf

20411-60-100-safety-datasheet.pdf