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Anti-Human CD282 (TLR2) PE

Anti-Human CD282 (TLR2) PE

Item no.	24911-60-25
Manufacturer	BioGems
Amount	25 tests
Category	Neuroscience Neural Lineage Markers Antibodies Flow Cytometry Primary Antibodies Neurodegeneration Markers
Type	Antibody
Format	PE
Applications	FC
Clone	TL2.1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Conjugate/Tag	PE
Citations	Flo, T. H., Halaas, A., Lien, E., Ryan, L., Teti, G., Golenbock, D. T., ... & Espevik, T. (2000). Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.The Journal of Immunology, 164(4), 2064-2069. Lien, E., Sellati, T. J., Yoshimura, A., Flo, T. H., Rawadi, G., Finberg, R. W., ... & Golenbock, D. T. (1999). Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Journal of Biological Chemistry, 274(47), 33419-33425. Cook, E. B., Stahl, J. L., Esnault, S., Barney, N. P., & Graziano, F. M. (2005). Toll-like receptor 2 expression on human conjunctival epithelial cells: a pathway for< i> Staphylococcus aureus</i> involvement in chronic ocular proinflammatory responses. Annals of Allergy, Asthma & Immunology, 94(4), 486-497.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The TL2.1 monoclonal antibody specifically reacts with human CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on peripheral blood monocytes and is involved distinguishing bacterial lipoproteins. The TL2.1 antibody blocks the receptor and immunoprecipitates TLR2 from human mammary epithelial cells (HMEC) and peripheral blood mononuclear cells (PBMC).
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

24911-60-25-datasheet.pdf

24911-60-25-safety-datasheet.pdf