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Anti-Human/Mouse CD282 (TLR2) SAFIRE Purified

Anti-Human/Mouse CD282 (TLR2) SAFIRE Purified

Item no.	24921-25-50
Manufacturer	BioGems
Amount	50 ug
Category	Neuroscience Neural Lineage Markers Antibodies Flow Cytometry Primary Antibodies Neurodegeneration Markers
Type	Antibody
Format	SAFIRE (Functional)
Applications	FC
Clone	T2.5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Vinnakota, K., Hu, F., Ku, M. C., Georgieva, P. B., Szulzewsky, F., Pohlmann, A., ... & Kettenmann, H. (2013). Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion. Neuro-oncology,15(11), 1457-1468. Meng, G., Rutz, M., Schiemann, M., Metzger, J., Grabiec, A., Schwandner, R., ... & Kirschning, C. J. (2004). Antagonistic antibody prevents toll-like receptor 2-"driven lethal shock-like syndromes. Journal of Clinical Investigation, 113(10), 1473-1481.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on monocytes, macrophages, dendritic cells, and the RAW264.7 cell line and is involved distinguishing bacterial lipoproteins.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity
Format	SAFIRE (Functional)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 10/23/2025

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